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哈佛醫(yī)學(xué)院波士頓兒童醫(yī)院醫(yī)生、丹娜法伯癌癥研究院醫(yī)生、哈佛醫(yī)學(xué)院兒科助理教授。

【專長領(lǐng)域】

非典型畸胎樣/橫紋樣腫瘤

腦腫瘤

脈絡(luò)叢腫瘤

DIPG 彌漫性腦橋膠質(zhì)瘤

室管膜瘤

生理細(xì)胞腫瘤的腦

膠質(zhì)瘤

成神經(jīng)管細(xì)胞

【從醫(yī)成就】(摘選)

Healthgrades 榮譽榜

【教育背景】?？婆嘤?xùn)

天普大學(xué)醫(yī)學(xué)院取得醫(yī)學(xué)博士學(xué)位

達(dá)特茅斯醫(yī)學(xué)院希區(qū)柯克紀(jì)念醫(yī)院住院醫(yī)住院醫(yī)培訓(xùn)

圣猶達(dá)兒童研究醫(yī)院專科培訓(xùn)

【學(xué)術(shù)著作】(摘選)

The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants.Pajtler KW, Mack SC, Ramaswamy V, Smith CA, Witt H, Smith A, Hansford JR, von Hoff K, Wright KD, Hwang E, Frappaz D, Kanemura Y, Massimino M, Faure-Conter C, Modena P, Tabori U, Warren KE, Holland EC, Ichimura K, Giangaspero F, Castel D, von Deimling A, Kool M, Dirks PB, Grundy RG, Foreman NK, Gajjar A, Korshunov A, Finlay J, Gilbertson RJ, Ellison DW, Aldape KD, Merchant TE, Bouffet E, Pfister SM, Taylor MD. Acta Neuropathol. 2017 Jan;133(1):5-12.

目前關(guān)于顱內(nèi)室管膜瘤的臨床管理及其獨特的分子變異的共識。

New chemotherapy strategies and biological agents in the treatment of childhood ependymoma. Wright KD, Gajjar A. Childs Nerv Syst. 2009 Oct;25(10):1275-82.

新的化療策略和生物制劑治療兒童室管膜瘤。

Molecular profiling of pediatric brain tumors: insight into biology and treatment. Johnson R, Wright KD, Gilbertson RJ. Curr Oncol Rep. 2009 Jan;11(1):68-72.

兒科腦腫瘤的分子譜：對腫瘤生物學(xué)及治療的見解。

Rethinking childhood ependymoma: a retrospective, multi-center analysis reveals poor long-term overall survival. Marinoff AE, Ma C, Guo D, Snuderl M, Wright KD, Manley PE, Al-Sayegh H, Sinai CE, Ullrich NJ, Marcus K, Haas-Kogan D, Goumnerova L, London WB, Kieran MW, Chi SN, Fangusaro J, Bandopadhayay P. J Neurooncol. 2017 Oct;135(1):201-211.

重新思考兒童室管膜瘤：回顧性，多中心分析顯示長期總體生存率不佳。

Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors. Ramkissoon SH, Bandopadhayay P, Hwang J, Ramkissoon LA, Greenwald NF, Schumacher SE, O'Rourke R, Pinches N, Ho P, Malkin H, Sinai C, Filbin M, Plant A, Bi WL, Chang MS, Yang E, Wright KD, Manley PE, Ducar M, Alexandrescu S, Lidov H, Delalle I, Goumnerova LC, Church AJ, Janeway KA, Harris MH, MacConaill LE, Folkerth RD, Lindeman NI, Stiles CD, Kieran MW, Ligon AH, Santagata S, Dubuc AM, Chi SN, Beroukhim R, Ligon KL. Neuro Oncol. 2017 Jul 1;19(7):986-996.

臨床靶向基于外顯子組的測序與全基因組拷貝數(shù)分析相結(jié)合：203個小兒腦腫瘤的精準(zhǔn)醫(yī)學(xué)分析。