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丹娜-法伯癌癥研究所哈佛醫(yī)學(xué)院醫(yī)學(xué)臨床路徑醫(yī)學(xué)主任

哈佛醫(yī)學(xué)院助理教授

【專長領(lǐng)域】

小細(xì)胞肺癌

非小細(xì)胞肺癌

間皮瘤

胸腺腫瘤

【教育背景】?？婆嘤?xùn)

布朗大學(xué)醫(yī)學(xué)院取得醫(yī)學(xué)博士學(xué)位。隨后，他在Beth Israel Deaconess醫(yī)學(xué)中心完成內(nèi)科住院醫(yī)師，并在Dana-Farber / Partners CancerCare完成醫(yī)學(xué)腫瘤學(xué)研究。

【學(xué)術(shù)著作】(摘選)

Expression of PD-1 and Its Ligands, PD-L1 and PD-L2, in Smokers and Never Smokers with KRAS-Mutant Lung Cancer.

Calles A, Liao X, Sholl LM, Rodig SJ, Freeman GJ, Butaney M, Lydon C, Dahlberg SE, Hodi FS, Oxnard GR, Jackman DM, J?nne PA. J Thorac Oncol. 2015 Dec;10(12):1726-35.

在患有KRAS突變肺癌的吸煙者和從不吸煙者中表達(dá) PD-1 及其配體PD-L1 和 PD-L2。

A phase I trial of high dose gefitinib for patients with leptomeningeal metastases from non-small cell lung cancer.

Jackman DM, Cioffredi LA, Jacobs L, Sharmeen F, Morse LK, Lucca J, Plotkin SR, Marcoux PJ, Rabin MS, Lynch TJ, Johnson BE, Kesari S. Oncotarget. 2015 Feb 28;6(6):4527-36.

大劑量吉非替尼治療非小細(xì)胞肺癌的軟腦膜轉(zhuǎn)移的 I 期試驗(yàn)。

Impact of epidermal growth factor receptor and KRAS mutations on clinical outcomes in previously untreated non-small cell lung cancer patients: results of an online tumor registry of clinical trials.

Jackman DM, Miller VA, Cioffredi LA, Yeap BY, J?nne PA, Riely GJ, Ruiz MG, Giaccone G, Sequist LV, Johnson BE. Clin Cancer Res. 2009 Aug 15;15(16):5267-73.

表皮生長因子受體和 KRAS 突變對以前未治療的非小細(xì)胞肺癌患者臨床結(jié)果的影響: 臨床試驗(yàn)的在線腫瘤登記結(jié)果。

Erlotinib plus bevacizumab in previously treated patients with malignant pleural mesothelioma.

Jackman DM, Kindler HL, Yeap BY, Fidias P, Salgia R, Lucca J, Morse LK, Ostler PA, Johnson BE, J?nne PA. Cancer. 2008 Aug 15;113(4):808-14.

厄洛替尼聯(lián)合貝伐單抗治療惡性胸膜間皮瘤

Small-cell lung cancer.

Jackman DM, Johnson BE. Lancet. 2005 Oct 15-21;366(9494):1385-96. Review.

小細(xì)胞肺癌